Papers of The 7th Japan Scar Workshop

6. Experience of Saireitou for the treatment of hypertrophic scars and keloids

Yasuyoshi Tosa1, Tomoaki Kuroki1, Nobuhiro Satoh1, Taro Kusano1, Shinya Yoshimoto1
1:Department of Plastic and Reconstructive Surgery, Showa University School of Medicine, Tokyo, Japan

Hypertrophic scars and keloids are elevated lesions in human skin that are caused by trauma, surgery or burns, although the details are still unknown. Complete response with a single therapy is difficult, and treatment depends on combinations of multiple therapies, including oral or topical steroids, silicone attachment, oral tranilast, compression therapy, surgical treatment, and electron beam radiation therapy. We used saireito for patients with hypertrophic scars or keloids, and efficacy was observed with improvement in all cases. In addition, there were no adverse drug reactions. Saireito consists of shosaikoto and goreisan, and a 9-gram daily dose contains 6 grams of the powdered extract of a mixture of twelve crude drugs. Among them, saireito has anti-inflammatory effects. A feature of saireito is that it is not contraindicated in women during pregnancy or lactation, although careful administration is required. Its usefulness can be expected in the group which requires ongoing oral therapy. Here, we report representative cases.
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