Papers of The 2nd Japan Scar Workshop

15. Histological characteristics of scars, hypertrophic scars, and keloids

Miki Izumi,
Department of Diagnostic Pathology, Tokyo Medical University, Tokyo, Japan

In general, scars form at sites of injury as a result of proliferation of thick collagen fibers. Hypertrophic scars and keloids proliferate beyond the range of the injury and create well-demarcated nodular lesions. Hypertrophic scars show characteristic parallel, nodular, or whirl structures. In keloids, pathognomonic keloid fibers are characterized by broad acidic bands of collagen proliferating haphazardly. The pathological differences between the etiologies (pierced keloid, acne keloidalis, etc), inter/intra lesion sites, and chronology should be further investigated.
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